Cognitive dysfunctions and pathological gambling in patients with Parkinson's disease
Identifieur interne : 000B35 ( Main/Exploration ); précédent : 000B34; suivant : 000B36Cognitive dysfunctions and pathological gambling in patients with Parkinson's disease
Auteurs : Gabriella Santangelo [Italie] ; Carmine Vitale [Italie] ; Luigi Trojano [Italie] ; Francesca Verde [Italie] ; Dario Grossi [Italie] ; Paolo Barone [Italie]Source :
- Movement Disorders [ 0885-3185 ] ; 2009-04-30.
English descriptors
Abstract
The purpose of this study was to investigate the neuropsychological correlates of pathological gambling (PG) in Parkinson's disease (PD). Fifteen patients with PD affected by PG (identified based on DSM‐IV criteria; PD+PG) without clinically evident dementia were compared with 15 nondemented patients with PD not affected by PG (PD−PG). Two groups of patients with PD were matched for age, length of education, and gender. Clinical and neuropsychiatric features were assessed; several cognitive domains, mainly related to executive functions, were explored by means of standardized neuropsychological tasks. PD+PG and PD−PG did not differ on clinical and neuropsychiatric aspects. PD+PG patients performed significantly worse than PD−PG patients on cognitive tasks that evaluated visuo‐spatial long‐term memory and several frontal lobe functions. After Bonferroni correction, differences remained significant on the Frontal Assessment Battery (FAB) (P = 0.001), on phonological fluency task (P = 0.003), and on the Trail Making Test, part B minus part A (P = 0.002). Logistic regression analysis demonstrated that low scores on the FAB were the only independent predictor of PG (odds ratio, 27.9; 95% CI: 2.82–277.95, P = 0.004). The results indicate an association between PG and frontal lobe dysfunctions in nondemented patients with PD. Low scores on the FAB indicate patients with PD at high risk for PG. © 2009 Movement Disorder Society
Url:
DOI: 10.1002/mds.22472
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Cognitive dysfunctions and pathological gambling in patients with Parkinson's disease</title><author><name sortKey="Santangelo, Gabriella" sort="Santangelo, Gabriella" uniqKey="Santangelo G" first="Gabriella" last="Santangelo">Gabriella Santangelo</name></author><author><name sortKey="Vitale, Carmine" sort="Vitale, Carmine" uniqKey="Vitale C" first="Carmine" last="Vitale">Carmine Vitale</name></author><author><name sortKey="Trojano, Luigi" sort="Trojano, Luigi" uniqKey="Trojano L" first="Luigi" last="Trojano">Luigi Trojano</name></author><author><name sortKey="Verde, Francesca" sort="Verde, Francesca" uniqKey="Verde F" first="Francesca" last="Verde">Francesca Verde</name></author><author><name sortKey="Grossi, Dario" sort="Grossi, Dario" uniqKey="Grossi D" first="Dario" last="Grossi">Dario Grossi</name></author><author><name sortKey="Barone, Paolo" sort="Barone, Paolo" uniqKey="Barone P" first="Paolo" last="Barone">Paolo Barone</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:B11ECA2CF47A6B8F4FBAB0D7C2E2CAFD00AA7F9B</idno><date when="2009" year="2009">2009</date><idno type="doi">10.1002/mds.22472</idno><idno type="url">https://api.istex.fr/document/B11ECA2CF47A6B8F4FBAB0D7C2E2CAFD00AA7F9B/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">000577</idno><idno type="wicri:Area/Main/Curation">000502</idno><idno type="wicri:Area/Main/Exploration">000B35</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Cognitive dysfunctions and pathological gambling in patients with Parkinson's disease</title><author><name sortKey="Santangelo, Gabriella" sort="Santangelo, Gabriella" uniqKey="Santangelo G" first="Gabriella" last="Santangelo">Gabriella Santangelo</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Scienze Neurologiche, Università di Napoli Federico II, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratorio di Neuropsicologia, Dipartimento di Psicologia, Seconda Università Studi di Napoli, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto di Diagnosi e Cura “Hermitage Capodimonte,” Naples</wicri:regionArea><wicri:noRegion>” Naples</wicri:noRegion></affiliation></author><author><name sortKey="Vitale, Carmine" sort="Vitale, Carmine" uniqKey="Vitale C" first="Carmine" last="Vitale">Carmine Vitale</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Scienze Neurologiche, Università di Napoli Federico II, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto di Diagnosi e Cura “Hermitage Capodimonte,” Naples</wicri:regionArea><wicri:noRegion>” Naples</wicri:noRegion></affiliation></author><author><name sortKey="Trojano, Luigi" sort="Trojano, Luigi" uniqKey="Trojano L" first="Luigi" last="Trojano">Luigi Trojano</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratorio di Neuropsicologia, Dipartimento di Psicologia, Seconda Università Studi di Napoli, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Verde, Francesca" sort="Verde, Francesca" uniqKey="Verde F" first="Francesca" last="Verde">Francesca Verde</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratorio di Neuropsicologia, Dipartimento di Psicologia, Seconda Università Studi di Napoli, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Grossi, Dario" sort="Grossi, Dario" uniqKey="Grossi D" first="Dario" last="Grossi">Dario Grossi</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratorio di Neuropsicologia, Dipartimento di Psicologia, Seconda Università Studi di Napoli, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Barone, Paolo" sort="Barone, Paolo" uniqKey="Barone P" first="Paolo" last="Barone">Paolo Barone</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Scienze Neurologiche, Università di Napoli Federico II, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2009-04-30">2009-04-30</date><biblScope unit="volume">24</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="899">899</biblScope><biblScope unit="page" to="905">905</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">B11ECA2CF47A6B8F4FBAB0D7C2E2CAFD00AA7F9B</idno><idno type="DOI">10.1002/mds.22472</idno><idno type="ArticleID">MDS22472</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson's disease</term><term>executive functions</term><term>frontal lobe</term><term>pathological gambling</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The purpose of this study was to investigate the neuropsychological correlates of pathological gambling (PG) in Parkinson's disease (PD). Fifteen patients with PD affected by PG (identified based on DSM‐IV criteria; PD+PG) without clinically evident dementia were compared with 15 nondemented patients with PD not affected by PG (PD−PG). Two groups of patients with PD were matched for age, length of education, and gender. Clinical and neuropsychiatric features were assessed; several cognitive domains, mainly related to executive functions, were explored by means of standardized neuropsychological tasks. PD+PG and PD−PG did not differ on clinical and neuropsychiatric aspects. PD+PG patients performed significantly worse than PD−PG patients on cognitive tasks that evaluated visuo‐spatial long‐term memory and several frontal lobe functions. After Bonferroni correction, differences remained significant on the Frontal Assessment Battery (FAB) (P = 0.001), on phonological fluency task (P = 0.003), and on the Trail Making Test, part B minus part A (P = 0.002). Logistic regression analysis demonstrated that low scores on the FAB were the only independent predictor of PG (odds ratio, 27.9; 95% CI: 2.82–277.95, P = 0.004). The results indicate an association between PG and frontal lobe dysfunctions in nondemented patients with PD. Low scores on the FAB indicate patients with PD at high risk for PG. © 2009 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Italie</li></country></list><tree><country name="Italie"><noRegion><name sortKey="Santangelo, Gabriella" sort="Santangelo, Gabriella" uniqKey="Santangelo G" first="Gabriella" last="Santangelo">Gabriella Santangelo</name></noRegion><name sortKey="Barone, Paolo" sort="Barone, Paolo" uniqKey="Barone P" first="Paolo" last="Barone">Paolo Barone</name><name sortKey="Grossi, Dario" sort="Grossi, Dario" uniqKey="Grossi D" first="Dario" last="Grossi">Dario Grossi</name><name sortKey="Santangelo, Gabriella" sort="Santangelo, Gabriella" uniqKey="Santangelo G" first="Gabriella" last="Santangelo">Gabriella Santangelo</name><name sortKey="Santangelo, Gabriella" sort="Santangelo, Gabriella" uniqKey="Santangelo G" first="Gabriella" last="Santangelo">Gabriella Santangelo</name><name sortKey="Trojano, Luigi" sort="Trojano, Luigi" uniqKey="Trojano L" first="Luigi" last="Trojano">Luigi Trojano</name><name sortKey="Verde, Francesca" sort="Verde, Francesca" uniqKey="Verde F" first="Francesca" last="Verde">Francesca Verde</name><name sortKey="Vitale, Carmine" sort="Vitale, Carmine" uniqKey="Vitale C" first="Carmine" last="Vitale">Carmine Vitale</name><name sortKey="Vitale, Carmine" sort="Vitale, Carmine" uniqKey="Vitale C" first="Carmine" last="Vitale">Carmine Vitale</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000B35 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000B35 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:B11ECA2CF47A6B8F4FBAB0D7C2E2CAFD00AA7F9B
|texte= Cognitive dysfunctions and pathological gambling in patients with Parkinson's disease
}}
| This area was generated with Dilib version V0.6.23. |  |